Polynucleotides in Aesthetic Medicine: Everything You Need to Know

Regenerative medicine is all about repairing, replacing, or regenerating cells, tissues, or organs to restore their function. The basic principle involves giving your body a boost to heal itself from any damage or signs of ageing. Regenerative medicine is an expanding field within aesthetics, with exciting treatments like exosomes and polynucleotides being the talk of the town.

So what exactly are polynucleotides and how do they work?

Let’s find out!

What are Polynucleotides?

To put it simply, polynucleotides are chains of nucleotides like DNA or RNA. These little superheroes are molecules that stimulate fibroblasts, the cells responsible for producing collagen and maintaining the structure of your skin. As we age, the function of fibroblasts decreases, resulting in less collagen production and, you guessed it, more wrinkles. But when polynucleotides are injected into your skin, they jumpstart the regeneration process, making your fibroblasts work their magic again.

Not only do polynucleotides boost collagen production, but they are thought to improve elasticity, increase hydration, and plump. On top of all this, they are powerful antioxidants and have anti-inflammatory properties. They're like a one-stop solution for various skin concerns. And the best part? They have minimal side effects, like temporary redness and swelling, which disappear in no time.

How Are They Used in Aesthetic Medicine?

Polynucleotides are administered through injections, and the process is quick and relatively painless. Depending on the area being treated, the average volume injected per side of the face is around 1ml. You may need a few treatments spaced a few weeks apart to achieve optimal results!

Clinical studies have shown improvements in hydration, elasticity, and collagen production after polynucleotide treatments. And the results typically last between 6 and 9 months, so you can enjoy your rejuvenated skin for quite a while.

They have become an increasingly popular under-eye treatment, targeting an area that is notoriously difficult to address.

 

What is the Evidence?

Clinical studies have shown improvements in hydration, elasticity, and collagen production after polynucleotide treatments. And the results typically last between 6 and 9 months.

However it is important to note that this area is still in its infancy, and research is ongoing.

Check out our summary slides below:

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